Cacna1a CLIA Kit for Mouse(Mus musculus) | EIAab.comCacna1a CLIA Kit for Mouse(Mus musculus)

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Cacna1a (Gene name),

Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Protein name ), CAC1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cacna1a(Caca1a;Cach4;Cacn3;Cacnl1a4;Ccha1a);

Protein name:

Voltage-dependent P/Q-type calcium channel subunit alpha-1A;

Alternative:

Calcium channel, L type, alpha-1 polypeptide isoform 4;Brain calcium channel I(BI);Voltage-gated calcium channel subunit alpha Cav2.1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity. Interacts with CABP1.

Function:

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

2368

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TARRGAHDAY | SESEDDWC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF08763

String:

P97445

SMR:

P97445

UniGene:

Mm.334658

KEGG:

mmu:12286

Uniprot:

P97445

FOR

ELISA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344r

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96T

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ELISA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

ELISA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

E1344m

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Packing:

96T

CLIA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344h

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Manual:

Looking for manual.

MSDS:

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96T

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CLIA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

MSDS:

Please sign in first.

CLIA Kit for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

U1344m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Cat.:

P1344Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Monoclonal Antibody for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Protein for Mouse Voltage-dependent P/Q-type calcium channel subunit alpha-1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Molecular identity of P-type calcium current in Purkinje neurons."
Richards K.S. , Swensen A.M. , Lipscombe D.
Submitted (2004-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Swiss Webster.
tissue: Brain.
2.

"Absence epilepsy in tottering mutant mice is associated with calcium channel defects."
Fletcher C.F. , Lutz C.M. , O'Sullivan T.N. , Shaughnessy J.D. Jr. , Hawkes R. , Frankel W.N. , Copeland N.G. , Jenkins N.A.
Cell87:607-617(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 49-2212;VARIANT TG LEU-649
strain: DBA/2J.
3.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-792;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
4.

"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain cortex.

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